ADVANTIX SPOT ON*6PIP 40-60KG

Name
ADVANTIX SPOT-ON FOR DOGS OVER 40 KG UP TO 60 KG

Category
Ectoparasiticides, insecticides and repellents.

Active ingredients
Each 6.0 ml pipette contains. INSERT TABLE Excipient(s). Butylhydroxytoluene (E321): 6.0 mg. For the full list of excipients, see section 6.1.

Directions
For the treatment and prevention of flea infestations (Ctenocephalides canis, Ctenocephalides felis). Fleas on dogs are killed within one day of treatment. One treatment prevents further flea infestations for four weeks. The product can be used as part of a treatment strategy for flea allergy dermatitis (FAD). For the treatment of lice (Trichodectes canis). The product has persistent acaricidal and repellent efficacy against tick infestations (Rhipicephalus sanguineus and Ixodes ricinus for four weeks, and Dermacentor reticulatus for three weeks). Through its repellent and knockdown action on the Rhipicephalus sanguineus tick vector, the product reduces the likelihood of transmission of the pathogen Ehrlichia canis, thereby reducing the risk of canine ehrlichiosis. Risk reduction has been demonstrated in studies starting from the third day after application of the product and persists for 4 weeks. Ticks already present on the dog may not be killed within two days after treatment and may remain attached and visible. It is therefore recommended to remove any ticks already present on the dog at the time of treatment to prevent them from attaching and taking a blood meal. One treatment provides repellent (anti-feeding) activity against sandflies (Phlebotomus papatasi for two weeks and Phlebotomus perniciosus for three weeks), mosquitoes (Aedes aegypti for two weeks and Culex pipiens for four weeks), and horseflies (Stomoxys calcitrans) for four weeks. Reduction of the risk of infection with Leishmania infantum through transmission by sandflies (Phlebotomus perniciosus) for up to 3 weeks. The effect is indirect and determined by the product's activity against the vector.

Dosage
For cutaneous use only. Apply only to intact skin. The minimum recommended dose is: 10 mg/kg body weight (bw) imidacloprid and 50 mg/kg body weight (bw) permethrin. Dosage schedule for Advantix Spot-on. Dogs (kg body weight): >40 kg <= 60 kg; Trade name: Advantix Spot-on for dogs over 40 kg up to 60 kg; volume: 6.0 ml; imidacloprid: 10 - 15 mg/kg body weight; permethrin: 50 - 75 mg/kg body weight. For dogs >60 kg, the appropriate combination with the pipettes for other sizes should be used. To reduce reinfestation due to the appearance of new fleas, it is recommended to treat all dogs in the household. Other animals living in the same household should be treated with a suitable product. To further help reduce the environmental threat, the additional use of a suitable environmental treatment against adult fleas and their developing stages is recommended. The product remains effective if the animal gets wet. However, intense and prolonged exposure to water should be avoided. Frequent exposure to water may reduce the persistence of efficacy. In these cases, do not repeat the treatment more frequently than once a week. If the dog requires shampooing, it is best to do so before applying Advantix or at least two weeks after application to optimize the product's effectiveness. In the event of a lice infestation, a further veterinary visit is recommended 30 days after treatment, as some animals may require a second treatment. To protect a dog throughout the sandfly season, treatment should be continued as directed throughout. Remove one pipette from the package. Holding the pipette upright, twist and remove the cap. Turn the cap back on and replace the opposite end on the pipette. Twist the cap to break the seal and then remove the cap from the pipette. With the dog standing on all four legs, apply the entire contents of the Advantix pipette evenly to four spots on the top of the back, starting from the shoulders and ending at the base of the tail. At each spot, part the coat until the skin is visible. Place the tip of the pipette on the skin and squeeze gently to empty some of the solution onto the skin. Do not apply too much solution to any spot, as this may cause some of the solution to run down the dog's sides.

Conservation
Do not freeze. After opening the foil pouch, store in a dry place at a temperature not exceeding 30 degrees C. Shelf life of the product in the foil pouch: 3 years. Shelf life of the product after opening the foil pouch: 12 months (all pipettes must be used within 12 months of opening the foil pouch or before the expiration date printed on the pipette, whichever is shorter). Shelf life of the opened pipette: After opening, the entire contents of the pipette must be applied to the animal's skin.

Pregnancy and breastfeeding
It can be used during pregnancy and breastfeeding.