VENORUTON "1,000 MG GRANULES" 30 SACHETS"

Name
Venoruton 1000 mg powder for oral solution
Venoruton 500 mg film-coated tablets
Venoruton 2% gel
Oxerutine


What is it and what is it for?
Venoruton contains the active ingredient oxerutine, a substance obtained from the flowers and leaves of Sophora japonica, a member of the flavonoid family. Oxerutine has antioxidant properties and protects blood vessels.
Venoruton is indicated:
• venous insufficiency (a disease affecting the venous system, especially that of the lower limbs and the veins of the anal region (hemorrhoids) which can manifest itself, for example, with swelling, a sensation of heaviness, pain or cramps in the legs and feet);
• capillary fragility (easy breakage of capillaries which become visible on the skin and can cause spots and bruises)

Talk to your doctor if you do not feel better or if you feel worse, if the disorder occurs repeatedly, or if you notice any recent changes in its characteristics.


What you need to know before taking the medicine
Do not use Venoruton
If you are allergic to the active substance or any of the other ingredients of this medicine (listed in section 6).


Warnings and precautions
Talk to your doctor or pharmacist before using Venoruton.

You should not take Venoruton if you suffer from swelling in your legs caused by heart, kidney or liver disease.

If you experience skin irritation or allergic reactions while using Venoruton gel, especially with prolonged use, stop using Venoruton gel and contact your doctor who will give you appropriate treatment.

Children and adolescents
Venoruton should not be used in children and adolescents.


Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.

For 1000 mg powder for oral solution and Venoruton 500 mg film-coated tablets:

Rare side effects (may affect up to 1 in 1,000 people)
• stomach or intestinal disorders;
• air in the stomach (flatulence);
• diarrhea;
• stomach pain;
• difficult digestion (dyspepsia);
• skin rash;
• itching;
• hives.

Very rare side effects (may affect up to 1 in 10,000 people)
• severe allergic reactions even after the first intake (anaphylactoid reactions);
• allergic reactions (hypersensitivity reactions);
• dizziness;
• heachache;
• hot flashes;
• tiredness.

For Venoruton 2% gel:

Rare side effects (may affect up to 1 in 1,000 people)
• allergic reactions with the appearance of skin changes, which disappear when treatment is stopped.

Following the instructions in the package leaflet reduces the risk of side effects.

Reporting of side effects
If you experience any side effects, including any not listed in this leaflet, talk to your doctor or pharmacist. You can also report side effects directly via the national reporting system at: https://www.aifa.gov.it/content/segnalazionireazioni-avverse .
By reporting side effects you can help provide more information on the safety of this medicine.