ZEFLAVON 500 MG FILM-COATED TABLETS 30 TABLETS IN PVC/AL BLISTER

Name
ZEFLAVON 500 mg film-coated tablets
micronized flavonoids, such as diosmin and other flavonoids expressed as hesperidin


What is it and what is it used for?
Zeflavon is a vasoprotective agent. It increases venous tone and the resistance of small blood vessels.

Zeflavon is indicated in adults:
- for the treatment of symptoms related to chronic venous insufficiency of the lower limbs: heaviness in the legs, swelling in the legs, pain, nocturnal leg cramps (pain that occurs in the legs at night);
- for the treatment of functional symptoms related to acute hemorrhoidal crisis, such as pain, bleeding and swelling in the anal region.


What you need to know before taking the medicine
Do not take Zeflavon:
- if you are allergic to the active substances or to any of the other ingredients of this medicine (listed in section 6).


Warnings and precautions
Talk to your doctor or pharmacist before taking Zeflavon.

Chronic venous disease:
For venous insufficiency, treatment should be combined with a healthy lifestyle for best results. Avoid exposure to the sun, heat, prolonged standing, and being overweight. Walking and wearing special (compression) stockings improve circulation.

If your condition worsens during treatment, manifesting as inflammation of the skin or veins, hardening of the tissue under the skin, severe pain, skin ulcers, or atypical symptoms such as sudden swelling of one or both legs, talk to your doctor immediately.

Zeflavon does not help reduce swelling of the lower limbs if it is caused by heart, kidney, or liver disease.

Acute hemorrhoidal disease:
If you have an acute hemorrhoid attack, you can only take Zeflavon for a limited period of 7 days. If the symptoms of acute hemorrhoidal attack do not disappear within 7 days, talk to your doctor.

If your condition worsens during treatment, that is, if you notice increased bleeding from the rectum, blood in your stool, or have concerns about bleeding hemorrhoids, consult your doctor.

Treatment with Zeflavon does not replace specific treatment of other anal disorders.

If you have any questions, ask your doctor or pharmacist.

Children and adolescents
Zeflavon is not recommended for use in children and adolescents.


Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.

Common : May affect up to 1 in 10 people
Nausea, vomiting, diarrhea, dyspepsia.

Uncommon : may affect up to 1 in 100 people
Inflammation of the colon.

Rare : May affect up to 1 in 1,000 people
Headache, dizziness, malaise, rash, itching, hives.

Not known : frequency cannot be estimated from the available data
- Isolated edema of the face, lips, or eyelids in association with allergic symptoms.
Quincke's edema (rapidly developing swelling of the face, lips, mouth, tongue, or pharynx, which may be accompanied by difficulty breathing) may develop exceptionally.
- Abdominal pain.

Reporting of side effects
If you experience any side effects, including any not listed in this leaflet, talk to your doctor or pharmacist. You can also report side effects directly via the national reporting system at: https://www.aifa.gov.it/content/segnalazionireazioni-avverse .
By reporting side effects you can help provide more information on the safety of this medicine.